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The Efficacy of 3 different modes of Erbium:YAG 2,940-nm laser combined with Neodymium:YAG 1,064-nm laser for the Lower Eyelid Rejuvenatio

Phase 2
Completed
Conditions
Smooth
PIANO
Nd:YAG
DermatochalasisEye BagMeibomian Gland Dysfunction
Lower eyelid rejuvenation
Dermatochalasis
Laxity
Er:YAG
Meibomian Gland Dysfunction
Registration Number
TCTR20200413003
Lead Sponsor
Ratchadaphiseksomphot Endowment Fund
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
24
Inclusion Criteria

Volunteers aged 35 years old or older with eye bags

Exclusion Criteria

1. Female volunteers who are currently pregnant or breastfeeding
2. Volunteers who used topical retinoids in the last month
3. Volunteers who received any form of exogenous estrogen in the last month
4. Volunteers who had facial chemical peeling or dermabrasion in the last month
5. Volunteers who took oral isotretinoin in the last 6 months
6. Volunteers who had botulinum toxin treatment in the periorbital area in the last 6 months
7. Volunteers who had HA, collagen or fat filler in the periorbital area in the last 6 months
8. Volunteers who had light/laser, radiofrequency or ultrasound treatment in the periorbital area in the last 6 months
9. Volunteers who had blepharoplasty within the last 6 months
10. Volunteers who had underlying photo-sensitive diseases

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pictures Week 0, 4, 8, 12, 16, 24 Digital camera
Secondary Outcome Measures
NameTimeMethod
niqueness Score Week 0, 4, 8, 12, 16, 24 Digital camera,ViscoElasticity Week 0, 4, 8, 12, 16, 24 Cutometer,Melanin Index Week 0, 4, 8, 12, 16, 24 Antera camera,Erythema Index Week 0, 4, 8, 12, 16, 24 Antera camera,Meibomian Gland Dysfunction Week 0,16, 24 OSDI, Meibum quality score, Lipid layer thickness, Tear-break-up time, ocular surface staining
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