Looking for Minimum Dose to Induce Sympathectomy in Infraclavicular Brachial Plexus Block
试验速览
- 阶段
- 不适用
- 入组人数
- 66
- 主要终点
- Change of diameter of basilic vein and brachial artery
研究概览
简要总结
For patients who undergoing hemodialysis, it is important to have good AV fistula. One third of AV fistula usually fail during early stage. It is helpful to use nerve block to dilate the blood vessels and enhance the prognosis. But 0.2% Ropivacaine usually cause muscle weakness in present studies. The investigators hope to find the lowest concentration to provide sympathectomy without muscle weakness. Because the patients with hemodialysis usually have multiple co-morbidity, thus we choose patients with forearm fracture at the first place. With this result, the investigators can design further study for patients with hemodialysis. The investigators prefer proximal approach because brachial plexus run together in the cosctoclavicular space and show lower incidence of incomplete work.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 20-80 y/o, BW: 40-90 kilograms,ASA class I-III,No pre-existing neuropathy,Scheduled for upper limb surgery.
排除标准
- •Pre-existing neuropathy (ex: polyneuropathy)
- •History of allergy to xylocaine、ropivacaine、epinephrine
- •Emergent surgery
- •Coagulopathy
- •Patient who can not express themselves
结局指标
主要结局
Change of diameter of basilic vein and brachial artery
时间窗: Change from baseline diameter(pre-nerve block) at 48hour
Use ultrasound to measure the difference of diameter at different time point.
次要结局
- Motor block of upper limb(48hour post nerve block)
- Sensory block of upper limb(24hour post nerve block)
研究者
anchihhsu
Principal Investigator
Taipei Medical University WanFang Hospital
