Synbiotic effect on adult functional constipatio

Phase 3

Conditions: functional constipation.
Constipation, unspecified
K59.00

Registration Number: IRCT20200915048726N1

Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 180

Inclusion Criteria

Patients with functional constipation according to Rome (III) criteria.
Patients who do not change their diet during the study.
Over 18 years

Exclusion Criteria

Depression
systemic diseases such as diabetes, and inflammatory bowel disease
Constipation due to hypothyroidism and hypercalcemia
Surgeries such as prostate, bowel resection , and spine surgery
Recent weight loss
cancer
Requiring colonoscopy
Recent use of laxatives
Pregnancy and lactation
Alcohol and opium users
Recent use of steroids, anticholinergics, antidepressants, iron, statins, cholestyramine, Cox-2 inhibitor, and sulfosalazine

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of constipation. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Wexner constipation Scoring System.;Stool consistency. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Bristol scoring system.

Secondary Outcome Measures

Name	Time	Method
Side effects. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: evaluation checklist.;Remission. Timepoint: At the beginning of the study (before the intervention), 15, 30, and 45 days after the beginning. Method of measurement: Total scores obtained from Wexner and Bristol systems.