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临床试验/JPRN-UMIN000000925
JPRN-UMIN000000925招募中未知

A prospective study on the effects of gene polymorphisms on postoperative pain management in patients undergoing orthognathic surgery - A study on gene polymorphism effects on postoperative pain management

Tokyo Metropolitan Institute of Medical Science0 个研究点目标入组 300 人开始时间: 2007年12月3日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
入组人数
300

研究概览

简要总结

American Society of Human Genetics (ASHG) 59th Annual Meeting 12th International Congress of Human Genetics (ICHG) / American Society of Human Genetics (ASHG) 61st Annual Meeting Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 21th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 41th Annual Meeting Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 22th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 42th Annual Meeting Purine 2012 European Human Genetics Conference 2013 XXIst World Congress of Psychiatric Genetics Method of evaluating drug-sensitivity by analyzing the voltage-dependent Ca2+ channel gene Method of evaluating drug-sensitivity by analyzing the adrenergic receptor genes Method of evaluating drug-sensitivity and vulnerability to diseases by analyzing the cyclic-AMP response element-binding protein gene Method of evaluating drug-sensitivity by analyzing several genes related to analgesia Fukuda K, Hayashida M, Ide S, Saita N, Kokita Y, Kasai S, Nishizawa D, Ogai Y, Hasegawa J, Nagashima M, Tagami M, Komatsu H, Sora I, Koga H, Kaneko Y, Ikeda K. Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery. Pain. 2009 Dec 15;147(1-3):194-201. doi: 10.1016/j.pain.2009.09.004. Epub 2009 Sep 26. Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Aoki Y, Nishi A, Saita N, Koukita Y, Nagashima M, Katoh R, Satoh Y, Tagami M, Higuchi S, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Koga M, Arinami T, Kaneko Y, Hayashida M, Ikeda K. Genome-wide association study identifies a potent locus associated with human opioid sensitivity. Mol Psychiatry. 2014 Jan;19(1):55-62. doi: 10.1038/mp.2012.164. Epub 2012 Nov 27.

研究设计

研究类型
Observational

入排标准

年龄范围
15years-old 至 60years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • Patients less than 15 years and more than 60 years or those with severe complications

研究者

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