ew measurement method of glucagon in patients with heart disease
Not Applicable
- Conditions
- Patients with heart diseaes and non heart disease who had never diabetes
- Registration Number
- JPRN-UMIN000027624
- Lead Sponsor
- Gunma Prefectual Cardiovascular Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1.over HbA1c 8.0 percent 2.Uncontrol hemodynamics stage in heart disase 3.No informed consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference value of AUC (area under the curve) glucagon in patient with or without heart disease(Sandwich ELISA).75gOGTT(oral glucose tolerance test) during 4h method.
- Secondary Outcome Measures
Name Time Method 1.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA) in patients with or without heart disease. 2.Each 0 to 4h, difference value of glucagon (RIA) in patients with or without heart disease. 3.Difference value of AUC glucagon (RIA and Sandwich ELISA) in patients with heart disease. 4.Difference value of AUC glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 5.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients with heart disease. 6.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 7.Relation between each 0 to 4h and AUC value of glucagon (Sandwitc ELISA and RIA) in patients and cardiac functions(EF,E/A,E/E',rest and exercie heart rate, anaerobic threhsold, peak VO2, O2 pulse, PETCO2, minimum VE/VCO2, VE vs VCO2 slope)