Breast cancer biomarkers and treatment targets

Not Applicable

• Conditions: Breast cancer; Cancer; Malignant neoplasm of breast

• Registration Number: ISRCTN40576403
• Lead Sponsor: niversity Hospital Southampton (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-09-21
• Last Update Posted: 30 March 2020
• Study Completion: 2025-10-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 500

Inclusion Criteria

All tissue will be obtained from pre-existing sources (tissue bank, archival material surplus to diagnostic requirements, tissue microarrays generated for research purpose). There will be no active patient participation.

Exclusion Criteria

All tissue will be obtained from pre-existing sources (tissue bank, archival material surplus to diagnostic requirements, tissue microarrays generated for research purpose). There will be no active patient participation.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Anticipated outcomes from this study are expression levels of candidate biomarkers in breast cancer. The expression levels will be evaluated by various means, but of this study is to determine the optimum methods of biomarker validation.<br><br> Validate BAG-1 as a bimomarker in breast cancer<br>

Secondary Outcome Measures

Name	Time	Method
Identify other proteins related to BAG-1 as possible biomarkers in breast cancer and therapeutic targets