Cardiovascular Diseases in HIV-infected Subjects (HIV-HEART Study)

Completed

• Conditions: Detection of Frequency, Severity and Progression of Cardiovascular Diseases in Patients With HIV-infection.; Effect on Cardiovascular Risk and Life Quality by Age, Gender, Classic Cardiovascular Risk Factors,; HIV-specific Cardiovascular Risk Factors, Cardiovascular Medication, Antiretroviral Medication

• Registration Number: NCT01119729
• Lead Sponsor: University Hospital, Essen

Brief Summary

Human immunodeficiency virus (HIV) infection has been associated with a variety of cardiovascular diseases. Even most industrialised countries exhibit a growing and aging population of HIV-infected patients in the majority treated with antiretroviral drugs, the investigators still do not know much about the impact of cardiovascular diseases in this group of patients. The present study is an ongoing trial that was conducted as a prospective and multicentre survey, being schemed to analyse the frequency and clinical course of cardiac disorders in HIV-infected patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2010-05
• Study First Submitted: 2010-05-07
• Study First Submitted QC: 2010-05-07
• Last Update Submitted: 2010-05-07
• Study First Posted: 2010-05-10
• Last Update Posted: 2010-05-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 803

Inclusion Criteria

• Age > 18 years
• Known HIV-infection
• Outpatients
• Written informed consent

Exclusion Criteria

● Acute cardiovascular disease or unstable hemodynamic status in the three weeks before inclusion

• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of cardiovascular diseases		Prevalence of cardiovascular diseases including coronary artery disease, congestive heart failure, peripheral arterial disease, cerebrovascular events, and valvular diseases.

Secondary Outcome Measures

Name	Time	Method
Prevalence of cardiovascular disorders		Prevalence of cardiovascular disorders determined by electrocardiography, exercise testing, echocardiography, blood samples.

Trial Locations

Locations (5)

HIV Outpatients Department; 🇩🇪 Duisburg, NRW, Germany

Department of Dermatology, University Hospital of Bochum; 🇩🇪 Bochum, NRW, Germany

HIV Outpatient Department; 🇩🇪 Essen, NRW, Germany

Department of Dermatology, University Hospital of Essen; 🇩🇪 Essen, NRW, Germany

West German Heart Center Essen; 🇩🇪 Essen, NRW, Germany