Molecular basis of lymphatic dysplasia in childre

Completed

• Conditions: lymphedema; Hennekam syndrome; 10005330; 10025231

• Registration Number: NL-OMON38818
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 105

Inclusion Criteria

Patients
* Diagnosed with lymphatic dysplasia in infancy or early childhood
* Parents / caregivers of patients able to read and understand the written information
Parents
* Parents of patients with lymphatic dysplasia as a child
* Able to read and understand the written information

Exclusion Criteria

None

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Detection of further gene(s) causing lymphatic dysplasia in children. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Understanding the molecular and cellular mechanisms leading to the various<br /><br>manifestations of lymphatic dysplasia in children.<br /><br>- Increase of our understanding of lymph vessel formation in man</p><br>