The Neural Mechanisms involved in Conflict and Reward Processing

Recruiting

Conditions: gezonde brein
nvt

Registration Number: NL-OMON34864

Lead Sponsor: niversiteit Leiden

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 25

Inclusion Criteria

Adults female subjects (18-30 years of age) with no history of neurological disorder/disease and no counter-indications to MRI will be included in this study. All participants will be right-handed native Dutch speakers with normal vision or contact lenses

Exclusion Criteria

Potential participants will be prescreened for contraindications for fMRI, which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy (in females). They will additionally be prescreened for head trauma, history of neurological or psychiatric illness and/or use of psychotropic medications. We only investigate female subjects because previous research has shown that they are more sensitive to the reward stimuli used in our study (Azim et al., 2005). Given that humor appreciation often is mother-tongue specific, only native-Dutch speakers will be asked to participate in the study. Finally, left-handed individuals will be excluded from the study because some left-handers have substantially different brain organization relative to right-handers.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the significant clusters of brain activation<br /><br>associated with conflict, those associated with reward, and those associated<br /><br>with interactions between conflict and reward. The main behavioral study<br /><br>parameter is conflict-driven decreases in interference measured by response<br /><br>times as a function of reward (cf. Egner, 2007). </p><br>

Secondary Outcome Measures