Silent Threat: How Do Preoperative Albumin Levels Affect Outcomes in Geriatric Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 330
- 试验地点
- 1
- 主要终点
- Postoperative Complication Rate
研究概览
简要总结
This retrospective, single-center study aims to evaluate the impact of preoperative albumin levels on postoperative outcomes in geriatric patients (aged 65 and above) undergoing cancer surgery. The study will compare postoperative complication rates, length of hospital stay, and intensive care needs between patients with hypoalbuminemia and those with normal albumin levels.
详细描述
Malnutrition is a significant risk factor for postoperative complications in elderly cancer patients. Preoperative serum albumin is a key biomarker reflecting nutritional and inflammatory status. This study will retrospectively review the medical records of 330 geriatric patients (≥65 years) who underwent cancer surgery at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. Patients will be grouped according to preoperative albumin levels: Group 1 (<3.5 g/dL, hypoalbuminemia) and Group 2 (≥3.5 g/dL, normal). The primary aim is to compare postoperative complication rates, length of hospital stay, and intensive care requirements between these groups. The findings are expected to clarify the prognostic value of albumin and support individualized perioperative management in geriatric cancer surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 65 years or older
- •Diagnosed with cancer and underwent cancer surgery
- •Preoperative albumin level recorded before surgery
排除标准
- •Preoperative sepsis, severe infection, or active inflammatory disease
- •Emergency or palliative surgery
- •Missing preoperative albumin value
- •Incomplete medical records or follow-up data
结局指标
主要结局
Postoperative Complication Rate
时间窗: within 30 days after surgery
The proportion of patients experiencing any postoperative complication (including but not limited to pulmonary complications, infections, or other adverse events) within 30 days after surgery, as assessed by clinical records and standardized criteria (e.g., Clavien-Dindo classification)
次要结局
- Length of Hospital Stay(postoperative first 30 days)
- Postoperative Intensive Care Unit (ICU) Admission(immediately after the surgery)
- Length of ICU Stay(30 days after surgery)
- 30-day Postoperative Mortality(within 30 days after surgery)
- Incidence of Specific Postoperative Pulmonary Complications(30 days after surgery)
研究者
Mustafa Kemal ŞAHİN
M.D
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital