Effect of herbal combination of traditional medicine (Rahayesh majoon) in in opium addicts

Phase 3

Recruiting

• Conditions: Addiction.; Other psychoactive substance related disorders

• Registration Number: IRCT20231014059714N1
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1- Patients with addiction (diagnosis based on DSM-IV criteria) who are treated with methadone
Age 65-18 years
The patient has not yet reduced the dose
The patient should not take a high dose of methadone.
The patient should only receive methadone treatment
The patient's methadone treatment time is more than 6 months, that is, it has reached a point where it is no longer necessary to increase the dose for the patient (the patient is on a stable dose of methadone)
The patient should receive a dose of methadone below 50 cc daily

Exclusion Criteria

1. Every 7 days, the urine test for morphine, methamphetamine, hashish is checked, and if the test is positive, the patient is excluded from the study.
The presence of certain diseases including hypothyroidism or hyperthyroidism and...
High blood pressure (systolic pressure above 160 and diastolic pressure above 100 mmHg)
Taking psychiatric and nerve drugs while studying, such as benzodiazepines, antidepressants, etc.
Having psychotic symptoms6. Pregnant women
Pregnant women
Warfarin users
People who are allergic to reading and report side effects caused by taking medicine while studying
Use of anti-oxidant and anti-inflammatory drugs and supplements in the last 3 months and during the study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Withdrawal syndrome. Timepoint: At the beginning of the study, the second and fourth week of the study. Method of measurement: Clinical opiate withdrawal symptoms (COWS).;Craving. Timepoint: At the beginning of the study, the second and fourth week of the study. Method of measurement: Desire for Drug Questionnaire (DDQ craving).

Secondary Outcome Measures

Name	Time	Method
Sleep quality. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Pittsburgh Sleep Quality Index (PSQI).;Anxiety. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Beck Anxiety Inventory (BAI).;Depression. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: Beck Depression Inventory (BDI).;Sexual desire. Timepoint: The beginning of the study, the second and fourth week of the study. Method of measurement: (IIEF)International index of erectile function questionnaire.