Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis After Using Dexamethasone in Combination With Local Anesthesia by Two Different Techniques (Randomized Clinical Trial)
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Ain Shams University
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- visual analogue score (VAS) from 0 to 10
Study Overview
Brief Summary
The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups:
- Group I: buccinator injection of dexamethasone.
- Group II: buccal infiltration of dexamethasone.
- Group III (Control): IANB using local anesthesia only post operative pain will be evaluated subjectively by patients by VAS score after procedure immediately and follow up for 12, 24 and 72 hours and frequency of analgesic intake
Detailed Description
the previous studies used dexamethasone with LA to prolong the duration of nerve block , Dexamethasone is used in reducing intraoperative endodontic pain the study main aim is to overcome the problem of severe postoperative pain after endodontic treatment in patients with acute irreversible pulpitis by evaluating the effect of dexamethasone in two different techniques by giving dexamethasone injection of buccinator muscle, or dexamethasone as buccal infiltration, and comparing the results with inferior alveolar nerve block using local anesthesia only. pain score evaluated using VAS score preoperatively and postoperatively with different anesthetic techniques after endodontic treatment.and their effet on frequency of analgesic intake
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Both genders
- •Older than age of (18 to 60) years
- •Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study
- •Having a mandibular molar tooth with vital pulp
- •These patients were also suffering from symptomatic irreversible pulpitis ,intermittent or continuous sharp pain that lasts longer after removal of the stimulus
- •Patients with moderate to severe symptoms VAS≥4
Exclusion Criteria
- •Vulnerable group; pregnant females, mentally ill and diseased patientsetc.…
- •Patients irritable to local anesthesia
- •Patients who are supposed to take plain anesthesia
- •Use of analgesic or antibiotic within 6 hours before the visit
- •Absence of bleeding in the pulp chamber during cavity preparation
- •Severe periodontal disease b- Patients' randomization, allocation and blinding:
Arms & Interventions
control
no intervention
buccinator injected by DEX drug
patients will receive dexamethasone(2ml/8mg) 1ml per 30 sec slow injection at buccinator muscle as single injection preoperatively
Intervention: dexamethasone 8mg (Drug)
buccal infiltration by DEX drug
buccal infiltration of dexamethasone (8mg/2ml) as single injection preoperative
Intervention: dexamethasone 8mg (Drug)
Outcomes
Primary Outcomes
visual analogue score (VAS) from 0 to 10
Time Frame: postoperative 72 hours
VAS preoperative ,immediately postoperative,12hrs,24hrs,72hrs
Secondary Outcomes
No secondary outcomes reported
Investigators
Salma Medhat
MSc Student
Ain Shams University