Efficacy of topical curcumin on mild to moderate idiopathic carpal tunnel syndrome

Phase 1

Recruiting

• Conditions: Carpal tunnel syndrome.; Carpal tunnel syndrome

• Registration Number: IRCT20140221016666N3
• Lead Sponsor: Sari University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 January 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

Female patients aged 18-65 years old completed the informed consent form
Sign and symptoms of carpal tunnel syndrome: at least two symptoms or one symptom and one sign including: pain, paresthesia, hypoesthesia, numbness, positive phalen or tinel test
Electrodiagnostic evidence suggestive of mild to moderate idiopathic carpal tunnel syndrome

Exclusion Criteria

Positive history of the curcumin hypersensitivity
Failure to complete the information collection form
Cervical radiculopathy or brachial plexopathy, TOS,Protator teres syndrome, ulnar neuropathy
Clinical Signs or Electrodiagnostic evidence of Polyneuropathy
Rheumatologic disorders such as: rheumatoid arthritis, systemic sclerosis, Lupus, Amyloidosis and so on
Endocrine disorders: Diabetes, hypothyroid
Conditions that mimic carpal tunnel syndrome, such as multiple sclerosis
Pregnancy and lactation
Serious cardiovascular disease like heart failure and kidney disease
Intravenous injection or physiotherapy for the treatment of carpal tunnel syndrome over the past 6 months
A positive history of a severe trauma or fracture of the wrist
The inevitable use of corticosteroids or analgesic drugs
Patients with severe carpal tunnel syndrome based on clinical or electrodiagnostic evidence

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Boston questionnaire score and severity of pain according to VAS. Timepoint: Before intervention and Eighth week after treatment. Method of measurement: Boston questionnaire and VAS.;EMG-NCV parameters changes. Timepoint: Before intervention and Eighth week after treatment. Method of measurement: Electrodiagnostic.