To assess the therapeutic effect of two drugs Curcumin and Pirfenidone when used in the form of an ointment for the management of Oral Submucous Fibrosis ( A disease affecting the mucous membrane of the oral cavity)
Phase 3
- Conditions
- Health Condition 1: K135- Oral submucous fibrosis
- Registration Number
- CTRI/2022/08/044967
- Lead Sponsor
- Maulana Azad Institute of Dental Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Clinically & histopathologically proven cases of OSMF
Any subject of age group18 to 50 years.
Both males and females.
A positive history of chewing areca nut or one of its commercial preparation, difficulty in swallowing and chewing, and burning sensation on eating spicy foods.
Restricted mouth opening and changes in the oral mucous membrane including the presence of palpable vertical fibrous bands, stiffness and blanching.
Exclusion Criteria
Subjects with mouth opening less than 15mm.
Subjects with severe systemic disease.
Pregnant and nursing women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method