Fertility Outcomes of Ovarian Tissue Cryopreservation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 主要终点
- Surgical complications
研究概览
简要总结
With the advancement of assisted reproductive technology, more young cancer patients can consider having children. Ovaries and testes are important reproductive organs, and drugs, diseases, chemotherapy, and radiotherapy can all damage them. Reproductive preservation technology aims to protect patients whose reproductive ability has been damaged due to gonadotoxic drug therapy. Women can preserve their reproductive ability by freezing ovarian tissue cryopreservation so that they can have children in the future. Patients who have undergone or will undergo ovarian tissue cryopreservation in Hong Kong Children's Hospital will be invited to participate in the study. Here, we aim to evaluate the outcomes after ovarian tissue cryopreservation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 18 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients aged from 0-18 years old and diagnosed with cancer
- •Patients who have undergone or will undergo ovarian tissue cryopreservation in Hong Kong Children's Hospital
- •For patients under 18 years old, parents/legal guardians will be asked to further sign the consent for them.
排除标准
- •Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)
- •Male patients
结局指标
主要结局
Surgical complications
时间窗: 15 years
Surgical complications after ovarian tissue transplantation
Pregnancy rate
时间窗: 15 years
Pregnancy rate after ovarian tissue transplantation
次要结局
未报告次要终点
研究者
Chung Pui Wah Jacqueline
Associate Professor
Chinese University of Hong Kong