The Impact of Aerobic Exercise Training on Cardiopulmonary Exercise Capacity in Patients With Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- cardiopulmonary exercise test results
研究概览
简要总结
The goal of this observational study is to learn about the short-term effects of aerobic exercise in heart failure patients who were given exercise prescription with cardiopulmonary exercise stres test acocording to aerobic capacity . The main question it aims to answer is:
Does aerobic exercise increase aerobic capacity and quality of life Participants already taking aerobic capacity as part of their regular medical care for Heart failure will asses with cardiopulmonary exercise test and clinical questionaries about quality of life and depression-anxiety level before and after aerobic exercise treatment .
详细描述
The goal of this observational study is to learn about the short-term effects of aerobic exercise in heart failure patients who were given exercise prescription with cardiopulmonary exercise stres test acocording to aerobic capacity . The main question it aims to answer is:
Does aerobic exercise increase aerobic capacity and quality of life Participants already taking aerobic capacity as part of their regular medical care for Heart failure will asses with cardiopulmonary exercise test and clinical questionaries about quality of life and depression-anxiety level before and after aerobic exercise treatment .
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-75,
- •Diagnosed with compensated HF,
- •BMI 18-30 kg/m²,
- •LVEF < 0.4,
- •NYHA 2-3,
- •Clinical symptoms have been stable for at least 2 weeks, and the dose of angiotensin-converting enzyme inhibitor/angiotensin receptor antagonist/angiotensin receptor inhibitor, beta-blocker, aldosterone inhibitor, and other drugs has been stable for at least 2 weeks.
排除标准
- •History of a heart implant device within the last 6 weeks or a heart implant device or heart transplant plan within the next 12 months,
- •Acute coronary syndrome within the last 6 weeks, severe valvular heart disease, congenital heart disease, severe hypertrophic obstructive cardiomyopathy, acute myocarditis/pericarditis, intracardiac thrombosis, primary pulmonary hypertension,
- •Uncontrolled hypertension (systolic blood pressure >200 mmHg and/or diastolic blood pressure >110 mmHg),
- •Severe arrhythmias such as ventricular tachycardia, frequent multisource premature ventricular beats, high atrioventricular block, and significant QT interval prolongation during exercise testing,
- •Progressive dyspnea or
- •Loss of exercise endurance at rest within the last 3-5 days under low-intensity exercise load (<2 MET) who have suffered myocardial ischemia,
- •Patients with cognitive impairment.
结局指标
主要结局
cardiopulmonary exercise test results
时间窗: 6 weeks
gas exchange response: VE/VCO2: EQCO2: Ventilatory equivalent for carbon dioxide minute ventilation while the produced CO₂ is removed,
cardiovascular exercise test result: Gas exchange parameters:
时间窗: 6 weeks
PETCO₂ (partial end-tidal carbon dioxide), kilopascal
次要结局
- Short Form (36) Health Scale(6 weeks)
- Hospital Anxiety and Depression Scale(6 weeks)