Robot-aided system identification (ROBIN) of neural and non-neural contributors to ankle joint impedance in children with CP

Recruiting

• Conditions: brain damage; spasticity; 10010335

• Registration Number: NL-OMON44131
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 240

Inclusion Criteria

- children diagnosed with spastic uni-or bilateral CP or with spastic paresis
- aged between 6 and 18 years
- with an indication for treatment of suspected high leg muscle tone, by either administration of botuline toxine or intrathecal Baclofen, serial casting or selective dorsal rhizotomy

Exclusion Criteria

- additional medical problems interfering with joint neuromechanical characteristics
- range of motion (sagittal) of ankle smaller than 20 degrees
- cognitive / communicative unability to understand instructions
- insufficient mastery of the Dutch or English language

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary parameters are the neuromuscular parameters:<br /><br>- visco-elasticity<br /><br>- optimal muscle length<br /><br>- reflex torque </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary parameters are:<br /><br>- spasticity score<br /><br>- tonus score<br /><br>- range of motion<br /><br>- angle of catch<br /><br>- joint power<br /><br>- gait parameters (kinematics, kinetics and walking speed)<br /><br>- selectivity of motor control (SCALE)<br /><br>- the gross motor functioning measure (GMFM)<br /><br>- VAS score on pain and treatment satisfaction<br /><br><br /><br>- Muscle belly length and lengthening<br /><br>- Fascicle length and lengthening<br /><br>- Pennation angle<br /><br>- Tendon length and lengthening</p><br>