Effectiveness of Plasmaphersis on the treatment of paraquat poisoned patients
Phase 3
Recruiting
- Conditions
- Paraquat poisoning.Toxic effect of herbicides and fungicides, accidental (unintentional)T60.3X1
- Registration Number
- IRCT20200507047344N4
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Age over 18 years
Oral paraquat poisoning (confirmation of paraquat poisoning is determined by testing for urinary sodium dithionate test)
No more than 24 hours after poisoning
Satisfaction to participate in the study
Exclusion Criteria
Having coagulation disorders
Having a history of respiratory-lung diseases
Having a previous lung injury
Having seizures, loss of consciousness or coma
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: Before the intervention and the first, third, fifth days after the intervention and during the discharge from the hospital. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before the intervention and the first, third, fifth days after the intervention and during the discharge from the hospital. Method of measurement: Monitoring device.;Electrolytic parameters. Timepoint: Before the intervention and the first, third, fifth days after the intervention and during the discharge from the hospital. Method of measurement: Blood test.;Coagulation parameters. Timepoint: Before the intervention and the first, third, fifth days after the intervention and during the discharge from the hospital. Method of measurement: Blood test.
- Secondary Outcome Measures
Name Time Method Tachypnea. Timepoint: The first, third, fifth days after the intervention until discharge from the hospital. Method of measurement: Clinical examination.;Respiratory distress. Timepoint: The first, third, fifth days after the intervention until discharge from the hospital. Method of measurement: Clinical examination.;Hypocalcemia. Timepoint: The first, third, fifth days after the intervention until discharge from the hospital. Method of measurement: Clinical examination.