Writing About Experiences and Health in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Inflammatory activity
研究概览
简要总结
UCLA researchers looking for healthy females (age 60+) to participate in a study investigating how writing about your experiences may be related to your health.
Once a week for 6 weeks, participants will write about their experiences and fill out online questionnaires. Participants will also come to the UCLA campus for blood draws and to fill out questionnaires 3 times: once prior to the 6-week writing period, once immediately after the 6-week period, and once 2-months after the writing period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 60 Years 至 100 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy adults 60 years and older
排除标准
- •Following a structured telephone interview, participants with the following conditions will not be able to participate:
- •current smokers
- •active, uncontrolled medical disorders
- •chronic infection (e.g., Hepatitis C, HIV)
- •use of certain medications (e.g., hypnotic and psychotropic medication, steroid use, opioid use)
- •psychiatric disorders (e.g., current major depression, bipolar disorder)
- •body mass index (BMI) greater than 35
- •Other exclusion criteria may apply.
研究组 & 干预措施
Writing: Group 1
Subjects will be asked to write about experiences with familiar individuals in their lives.
干预措施: Writing: Group 1 (Behavioral)
Writing: Group 2
Subjects will be asked to write about experiences with familiar places in their lives.
干预措施: Writing: Group 2 (Other)
结局指标
主要结局
Inflammatory activity
时间窗: baseline, post 6-week writing period, 2-months post-writing period
Changes in proinflammatory cytokine and proinflammatory gene expression from blood draws
Health and well-being (self-report)
时间窗: baseline, post 6-week writing period, 2-months post-writing period
Changes in self-report measures of health (e.g., pain, sleep) and well-being (e.g., social support, depression)
次要结局
未报告次要终点
研究者
Naomi Eisenberger
Associate Professor
University of California, Los Angeles