A study of Repetitive transcranial magnetic stimulation augmentation in depressio

Phase 4

Completed

• Conditions: Health Condition 1: null- Depression

• Registration Number: CTRI/2017/10/010073
• Lead Sponsor: Jyoti Singh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-07-15
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 29

Inclusion Criteria

1.Diagnosis of depression based on ICD-10 DCR criteria (F32, F33)

2.Age 18-50 years

3.Treated with adequate dose of any antidepressant(s) for at least 4 weeks

4.Clinical Global Impression-Improvement (CGI-I) rating worse than/equal to 3 (as per treating Psychiatrist)

5.Montgomery Asberg Depression Rating Scale (MADRS) score in the range of at least moderate depression (>=20)

6.Written informed consent

Exclusion Criteria

1.Patients with suicidality

2.Depression with psychotic symptoms

3.Bipolar depression

4.Other co-morbid psychiatric disorder including substance use (except nicotine)

5.Medical co-morbidities requiring priority medical management

6.Presence of contra-indications to rTMS such as metallic implants, seizure disorder etc.

7.Pregnant females and lactating mothers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Montgomery Asberg Depression Rating ScaleTimepoint: Week 0, 1, 2, 3, 6

Secondary Outcome Measures

Name	Time	Method
clinical global impression scale both severity and improvementTimepoint: Baseline, 1, 2, 3 weeks