Comparsion the effects of Echinacea and normalsaline mouthwashes on Ventilator Associated Pneumonia in intubated patients in intensive care units. Arak
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 70
研究概览
简要总结
Abstract
Introduction: Ventilator associated pneumonia (VAP) is a problem threatening patients in Intensive Care Units and has a high prevalence. Mouthwash is a caring procedure which can decrease the rate of VAP. The present study aims to compare the effects of Echinacea and normal saline mouthwash on ventilator associated pneumonia prevalence.
Material and Methods: This is a clinical trial in which 70 intubated patients in intensive care units of educational hospitals in Arak city, were selected purposively and allocated in two intervention (Echinacea mouthwash) and control (normal saline mouthwash) groups randomly. VAP was diagnosed by completing Clinical Pulmonary Infection Scale (CPIS), before and at fifth day of the intervention. The rate of ventilator associated pneumonia was compared in the two groups. Data was analyzed using Chi square and t tests.
Results: The two groups were not significantly different regarding demographic characteristics. Ventilator associated pneumonia prevalence was 60% in normal saline and 51.4% in Echinacea group. There was no significant difference between the two groups.
Conclusion: Despite the lower rate of VAP in intervention group, results showed that this difference was not significant.
Keywords: Intensive care, mouthwash, Echinacea, normal saline, Ventilator associated pneumonia
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •having a tracheal tube; aged 18-65 years; less than 12 hours of hospitalization in the intensive care unit before.
- •Exclusion criteria: patients transferred from the intensive care unit; patients died before completion of the study; any damage caused by endotracheal intubation; airway or any other physical cause; antibiotic use before admission; admission in other units before intensive care unit; pregnancy; history of allergy to herbal substances; chronic diseases of immune system.
排除标准
- 未提供