A Clinical study ayurvedic medicines Chitrakadi Vati and Avipathi Churnam in the management of Hypothyroidism

Phase 2

Conditions: Health Condition 1: null- Hypothyroidism

Registration Number: CTRI/2017/10/010066

Lead Sponsor: Dr Anoop A S

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Diagnosis will be made on the basis of TSH value more than 15-20 mU/l which may or may not be associated with decrease in T3 and T4 concentration and also with the signs and symptoms of Hypothyroidism one or multiplicity of these viz

1.tiredness,

2.dryness of skin,

3.feeling cold

4.hair loss,

5.constipation,

6.Weight gain with poor appetite

7.Hoarseness of voice,

8.muscle ache or stiffness,

9.menstrual disturbances,

10.Bradycardia

11.periorbital puffiness.

Inclusion criteria include

1.Patients of age between 18 to 60 years of either gender

2.Patients already diagnosed as hypothyroidism with or without medication,

3.Patients with Primary hypothyroidism,

4.Patients with subclinical hypothyroidism,

5.Patients who are ready to sign the informed consent form

Exclusion Criteria

Exclusion criteria are as follows

1.Patients who have undergone any type of thyroid surgery,

2.Patients suffering from systemic diseases like Ischemic Heart Disease, Diabetes mellitus, carcinomas,

3.Patients suffering from congenital hypothyroidism,

4.Pregnancy and lactation,

5.Rapid progressive case of myxedema,

6.Hypothyroidism due to drug therapy (e.g. Amiodarone, Lithium, Interferon)

7.Hypothyroidism due to infiltrative diseases like Sarcoidosis,Scleroderma and Haemochromatosis

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of subjective parameters will be done on 1st day,10th day, 41st day, 71st day and 90th day with the help of a suitable clinical scoring of hypothyroidism â?? BILLEWICZ SCORE <br/ ><br>The parameters in BILLEWICZ SCORE are the following signs and symptoms: <br/ ><br>Symptoms are Diminished sweating,Dry skin,Cold intolerance,Weight increase, <br/ ><br>Constipation, Hoarseness of voice and <br/ ><br>Deafness <br/ ><br>Signs are Slow movements, Coarse skin, <br/ ><br>Cold skin, Periorbital puffiness, Pulse rate and Ankle jerk <br/ ><br>Timepoint: 90 DAYS

Secondary Outcome Measures