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临床试验/NCT04744233
NCT04744233已完成不适用

Effect of Traditional and Emerging Conservation Technologies on Bioactive Compounds and Their Antioxidant Capacity in Plant Foods

Instituto de Ciencia y Tecnología de Alimentos y Nutrición2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2001年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
12
试验地点
2
主要终点
Assessment of the effect of dairy intake of orange juice elaborated with four different procedures on the serum carotenoid concentrations of healthy adults.

研究概览

简要总结

Commercially available fruit juices are obtained after applying industrial technologies to preserve and extend the shelf-life by inactivation of microorganism and enzymes. These are traditional thermal treatment (eg. pasteurization, sterilization) that causes losses of nutritional and bioactive compounds, changes physicochemical properties (colour, flavor and texture) and can modify their bioavailabilities. Thus, the traditional thermal processing is being replaced by less intense thermal technologies (e.g. low-temperature pasteurization / refrigerated storage) and non-thermal treatments such as the high-pressure processing (HPP) and the pulsed electric fields (PEF) as an alternative to enhace food safety and shelf-life without compromising organoleptic qualities (retain the flavour, color healthiness of fresh foods) and keeping their health-promoting capacity. The beneficial health effect derived from the orange juice intake is partly related to the bioavailability of their bioactive compounds.

The aim of this study was to assess the effect of the intake of freshly squeezed orange juice (Citrus sinensis L.) and processed orange juice elaborated with different treatments (low pasteurization / refrigerated storage, high-pressure processing, pulsed electric fields) on the main serum carotenoid concentrations in a cross-over study in apparently healthy subjects using multiple dosis.

详细描述

Methods Twelve healthy subjects (6 men), age 20-32 y, were enrolled in a cross-over study, to consume 500 mL of orange juice/day during 14 days periods. All volunteers consumed the LP and HPP, six consumed PEF or FS-orange juice. Fasted blood was collected at baseline and on days 7 and 14. Carotenoid concentrations in serum and orange juice were analyzed by high performance liquid chromatogry (HPLC).

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
20 Years 至 32 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • age (20- 32 y)
  • body mass index (BMI)
  • serum cholesterol and triglycerides concentrations within the normal range
  • serum retinol within the range 31 - 70 µg/dL.

排除标准

  • vitamin / mineral supplements intake
  • regular medication
  • pregnancy or lactating
  • chronic disease
  • smoking habit.

结局指标

主要结局

Assessment of the effect of dairy intake of orange juice elaborated with four different procedures on the serum carotenoid concentrations of healthy adults.

时间窗: 6 months

Assessment of the effect of dairy intake of orange juice elaborated with low temperature pasterurization (LP), high-pressure processing (HPP), pulsed electric fields (PEF) and freshly squeezd (FS) on the serum carotenoid concentrations of healthy adults.

次要结局

未报告次要终点

研究者

发起方
Instituto de Ciencia y Tecnología de Alimentos y Nutrición
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Begoña Olmedilla

Research Scientist. Ph.D.

Instituto de Ciencia y Tecnología de Alimentos y Nutrición

研究点 (2)

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