A randomised, double-blind, parallel-group comparison of the efficacy and the safety of venlafaxine versus nortriptyline in the treatment of depressed elderly inpatients.
Completed
- Registration Number
- NL-OMON27258
- Brief Summary
1. Int J Geriatr Psychiatry. 2007 Dec;22(12):1247-54. <br>
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 81
Inclusion Criteria
1. Male or female inpatient;
2. Aged 60 years or older;
Exclusion Criteria
1. Known hypersensivity to venlafaxine or nortriptyline;
2. Previous unsuccessful treatment with venlafaxine for at least 4 weeks with a minimum dose of 75 mg/day or previous unsuccessful treatment with nortriptyline for at least 4 weeks with a serum level within the therapeutic range;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission on the MADRS (final score of 10 or less).
- Secondary Outcome Measures
Name Time Method Remission on HAM-D and GDS, response on MADRS, HAM-D and GDS, number of side effects, Global Tolerability Score, MMSE, Barthel ADL score, SF-20.