Evaluation of association of Parkinsons Disease symptoms with urinary extracellular vesicles

DrDinesh Upadhya0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

研究概览

暂无简介。

•Patients will be enrolled from neurology OPD of Kasturba Hospital Manipal.
•Patients satisfying the UK PD Brain Bank criteria for idiopathic PD will be included after clinical evaluation by a movement disorder specialist.
•Criteria includes bradykinesia and at least 1 of the following
•Muscular rigidity; 4-6Hz resting tremor; postural instability not caused by a primary visual
•,vestibular,cerebellar or proprioceptive dysfunction following the exclusion of other causes of Parkinsonism.
•Additionally, 3 or more features that supported a diagnosis of PD including: a unilateral onset and presence of a resting tremor, a progressive disorder,
•Persistent asymmetry maximally affecting the side of onset,
•Excellent response to levodopa and presence of severe levodopa induced chorea.

•atypical Parkinsonism, secondary Parkinsonism,
•h/o repeated Strokes, intake of antipsychotics,mini-mental state examination score <24, presence of cerebral tumor or communicating hydrocephalus,negative response to large doses of Levodopa(if malabsorption is excluded,exposure to 1-methyl4- phenyl2,3,6tetrahydropyridine(MPTP), patients who refused or were unable to give consent

发起方

DrDinesh Upadhya