The Effect of Oxygen Therapy on Atelectasis

Completed

• Conditions: Hypotension; Atelectasis; Cesarean Section
• Interventions: Diagnostic Test: lung ultrasound score

• Registration Number: NCT05509764
• Lead Sponsor: Zonguldak Bulent Ecevit University

Brief Summary

In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis. The development of atelectasis due to dermatomes retained in spinal anesthesia and intraoperative supine position may increase further. Oxygen therapy to be applied may also lead to absorption atelectasis by causing hyperoxia. The aim of our study is to evaluate the effect of oxygen support on the lungs in cesarean section operations under spinal anesthesia by lung ultrasound score and oxygen reserve index.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-01
• Primary Completion: 2022-03-01
• Status Verified: 2022-08
• Study Completion: 2022-08-01
• Study First Submitted: 2022-08-18
• Study First Submitted QC: 2022-08-18
• Study First Posted: 2022-08-22
• Last Update Submitted: 2022-08-22
• Last Update Posted: 2022-08-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1

Inclusion Criteria

• 18-50 years old
• ASA I-II
• Patients scheduled for elective cesarean section under spinal anesthesia

Exclusion Criteria

• alcohol or drug addiction, chronic obstructive pulmonary disease, cardiovascular disease, smokers anemia, liver or kidney disease, coagulation disorders allergic to anesthetic agents, sepsis or bacterial infection, body temperature is below 35°C and above 38°C Multiple pregnancy Preoperative hypoxemia SpO2<94% Diabetes mellitus Hypertension Placenta previa Premature rupture of membranes Intrauterine growth retardation Preeclampsia-eclampsia-fetal distress Polyhydramnios Morbid obesity BMI>45

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group 3	lung ultrasound score	3 Lt/min Oxygen therapy via nasal cannula
group 0	lung ultrasound score	control group
group 6	lung ultrasound score	6 Lt/min Oxygen therapy via Simple face mask

Primary Outcome Measures

Name	Time	Method
atelectasis	during the surgery	measuring atelectasis due to oxygen therapy

Secondary Outcome Measures

Name	Time	Method
APGAR score	1st and 5th min after delivery	baby status after delivery
hypotension	during surgery	maternal hypotension

Trial Locations

Locations (2)

Manolya Alkan; 🇹🇷 Zonguldak, Kozlu, Turkey

Zonguldak Bülent Ecevit University Medicine Faculty; 🇹🇷 Zonguldak, Kozlu, Turkey