NCT02386579已完成不适用
Characterization of Local and Systemic Bone Markers in Diabetes Patients With Charcot Osteoarthropathy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5
- 主要终点
- RANKL
研究概览
简要总结
The study is designed to investigate biomarkers related to bone turnover in diabetics with charcot foot. This is done by measuring local blood samples in the feet, and systemically in a vene and an artery. Measurements are done before and after cooling the feet in icewater to lower the bloodflow.
Patients will be compared with healthy diabetic controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diabetes mellitus type 1 or 2
- •Charcot foot diagnosed with x-ray, scintigraphy or clinical review by a specialist
排除标准
- •Osteoporosis
- •Anti-osteoporotic treatment
- •Lower extremity amputation
- •Lower extremity infection
结局指标
主要结局
RANKL
时间窗: 10 min between measurements
次要结局
- sRAGE(10 min between measurements)
- P1NP(10 min between measurements)
- osteocalcin(10 min between measurements)
- CTX-I(10 min between measurements)
研究者
相似试验
已完成
不适用
Markers of Bone Status in Diabetes Mellitus (Type 1 and Type 2)OsteopeniaDiabetes MellitusOsteoporosisNCT01870557Jakob Starup Linde197
进行中（未招募）
1 期
Markers of bonestatus in Diabetes Mellitus patients (type 1 and type 2) and the effect of antiresorptive treatment on glycemic markersCTIS2024-514148-99-00Aalborg University Hospital64
进行中（未招募）
1 期
Markers of bone in diabetics and the effect of bone treatment.Diabetes Mellitus and Osteopenia/OsteoporosisEUCTR2013-001222-26-DKAalborg University Hospital64
已完成
不适用
Evaluation of Bone Metabolism Biomarkers in Periodontal DiseasesPeriodontal DiseasesNCT05702892Necmettin Erbakan University60
已完成
4 期
Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate CancerProstate CancerNCT00391690Novartis99