A randomised controlled trial comparing efficacy of combined letrozole and clomiphene versus only letrozole as a method of ovulation induction in women with polycystic ovarian syndrome. - CCLOP

Dr Soumya Ranjan Panda0 个研究点目标入组 80 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Patients attending the infertility clinic in the Department of Obstetrics and Gynecology at AIIMS, Mangalagiri will be included in our study if the following inclusion criterias are fulfilled.
•1)The age of the patient is between 20 yrs to 40 yrs
•2)Diagnosed as PCOS according to Rotterdam critetria.
•3)a normal hysterosalpingogram or laparoscopy has been documented;
•4)no recorded history of pelvic surgery and/or pelvic inflammatory disease;
•5)Male partners having a normal semen analysis, according to the 2010 World Health Organization criteria, within the preceding 6 months and
•6)no history of treatment with exogenous gonadotropin.

•1)Endocrine factors other than anovulatory PCOS like hyperprolactinemia, hypothalamic amenorrhea, premature ovarian failure and ovarian tumor or clinical suspicion of other etiologies that mimic PCOS warranting additional evaluation.
•2)uncorrected thyroid disease; uncontrolled type 1 or 2 diabetes mellitus or hypertension.
•3)allergy or contraindications to letrozole or CC.
•4)Other associated factors of infertility like male factor, uterine factor and endometriosis.

发起方

Dr Soumya Ranjan Panda