Results of Endoscopic Sinus Surgery in Management of Ophthalmological Complications of Chronic Rhino Sinusitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- observe improvement of ophthalmological manifestation after surgical intervention
研究概览
简要总结
Investigate the clinical features of orbital complications of sinusitis in the Egyptian population, and observed that certain ophthalmological manifestations and outcomes were significantly associated with disease stage
详细描述
Retrospectively review of the medical records of all patients with orbital complications of paranasal sinusitis hospitalized at the ORL-HNS department at the University of Tanta between 2010 and 2020. Sex, age, symptoms, history, ophthalmological findings, laboratory and imaging findings, treatments, and outcomes were analyzed by staging.
The data that will be retrieved from the medical records including:
- History taking including personal present and previous medical history.
- General examination
- Oto-rhinolaryngological clinical examination
- Routine preoperative laboratory investigations (e.g. complete total and differential blood count, blood sugar, coagulation profile, and renal and liver function)
- Diagnostic nasal Endoscopy with zero and/or a 30-degree telescope.
- CT paranasal sinuses with contrast, fine cuts in coronal axial, and sagittal planes.
- The type of intervention whether medical or surgical. 8- Culture results, treatments, hospital stay durations, and outcomes.
Ophthalmology data collection:
- Visual acuity (onset of decrease) (unilateral or bilateral) ant its improvement after sinus surgery
- Presence or absence of double vision (Diplopia)
- Ocular motility and if its associated with pain
- Proptosis (present or absent) and calculate the degree and direction
- Ptosis (present or absent)
- Pupil reactivity
- Fundus examination to exclude optic nerve neuropathy
- Association between ocular pain and headache and its improvement after surgery
- CT data collection (CT orbit, MRI of sinus and head)
- Fundus photography after surgery to see improvement of optic nerve neuropathy if present
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Month 至 50 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient presented with preseptal/orbital inflammation secondary to acute (<1 month), subacute (1±3 months), or chronic sinusitis (>3 months) of bacterial, fungal or unidentified pathogens
排除标准
- •Patients with chronic rhinosinusitis without orbital complication, Systemic diseases that affect the paranasal sinuses and the orbit e.g autoimmune diseases, lymphoma, leukaemia, Sinus or orbital malignancy, Data is missed from the charts
研究组 & 干预措施
Treatment
干预措施: Endoscopic sinus evacuation (Procedure)
结局指标
主要结局
observe improvement of ophthalmological manifestation after surgical intervention
时间窗: 1 month
Measure the visual acuity by using Snellen chart and LogMAR chart (Logarithm of the minimum angle of resolution ) chart The Minimum number of snellen chart is 6/60 and maximum number is 6/6, The Minimum number of LogMAR chart is 1.0 and maximum number is - 0.1, The higher number means better vision
Improvement of the degree of proptosis after surgery
时间窗: 1 month
Decrease the degree of proptosis in millimeter
次要结局
未报告次要终点