Effect of Functional Endoscopic Sinus Surgery On Eustachian Tube Function in Patients With Nasal Polypi
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- The rate of Eustachian tube dysfunction with nasal polyp
研究概览
简要总结
This study is conducted to :
Correlate the incidence of ETD with nasal polypi. To evaluate the effects of functional endoscopic sinus surgery on eustachian tube function in patients with nasal polypi
详细描述
Eustachian tube dysfunction (ETD) is a frequently applied diagnosis, used when abnormal ET function is believed to underlie any of a wide range of symptoms or middle ear (ME) abnormalities. Two distinct forms of the disorder are recognised, representing different ends of the spectrum of ET function: 1)obstructive ETD (OETD), in which tubal opening or patency is reduced, and 2) patulous ETD (PETD), in which the ET is too open. It has been suggested that some patients with OETD have either predominantly active dysfunction (failure of muscle-controlled opening), or passive dysfunction (failure of pressure-related opening).
There are several explanations to account for the ET dysfunction associated with nasal diseases:
- Mechanical obstruction of ET orifice may occur due to nasal mass.
- Increased secretions from seromucous glands in the pharyngeal portion of ET may accumulate and block the tube.
- Lymphatic stasis due to edema of the submucosa of the tube resulting in compromise of the lumen may produce ET dysfunction.
- Further increase in hydrostatic pressure result in the accumulation of ME fluid by transudative process.
- Tubal dysfunction may be related to deficiency of surfactant that is thought to facilitate tubal opening. It has been postulated that this material is inactivated by inflammation.
ETD symptoms will decrease post-endoscopic sinus surgery to a level comparable with a non-CRS population The use of the ETDQ-7 has the potential to enhance clinical care by highlighting the impact of ETD as well as guiding and evaluating appropriate management. Further prospective testing of
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient Who have been diagnosed to have nasal polypi Both unilateral and bilateral before doing FESS
排除标准
- •children Patient. Patients with craniofacial abnormalities or active infection Patients with suspected nasal and nasopharyngeal tumour Patients with nasal and ear surgery
结局指标
主要结局
The rate of Eustachian tube dysfunction with nasal polyp
时间窗: 2years
次要结局
未报告次要终点
研究者
Safia Saleh Abdellattef
Assistant lecturer
Assiut University
