Setting up a Pediatric Cohort for Inflammatory Rheumatic Diseases
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Arthritis, Juvenile Rheumatoid
- Sponsor
- Michaël Hofer
- Enrollment
- 15000
- Locations
- 45
- Primary Endpoint
- Number of treatments prescribed off label
- Status
- Enrolling By Invitation
- Last Updated
- 2 years ago
Overview
Brief Summary
The investigators created a cohort of patients with juvenile inflammatory rheumatisms with the purpose to follow them prospectively, and investigate the tolerance and efficacy of immunosuppresive and biological agents.
Detailed Description
The JIR-cohort has to be filled by an authorized investigator during or after the consultation. Each patient much be followed at least once a year. Different data are requested in the JIR-cohort: diagnosis, treatment, adverse events and outcome.
Investigators
Michaël Hofer
Head of Pediatric Rheumatology unit
University of Lausanne Hospitals
Eligibility Criteria
Inclusion Criteria
- •Patients with juvenile inflammatory diseases
- •Age at onset up to 18 years old
- •Consent according national codes of ethics and current laws
Exclusion Criteria
- •Non-consent from patients and/or legal representative
Outcomes
Primary Outcomes
Number of treatments prescribed off label
Time Frame: 10 Years
Length in months of drug survival in patient treated with at least two consecutive biological agents
Time Frame: 10 Years
Number of severe and very severe adverse event as a mesure of safety and tolerability
Time Frame: 10 years