Timing of Intrauterine Insemination (IUI) 24 or 48 Hours After Spontaneous Luteinizing Hormone (LH) Peak

Phase 4

Completed

• Conditions: Pregnancy
• Interventions: Procedure: intra-uterine insemination

• Registration Number: NCT01622023
• Lead Sponsor: Universitair Ziekenhuis Brussel

Brief Summary

The aim of the present study is to prospectively evaluate whether performing an intra-uterine insemination 24 hours after the spontaneous LH peak may result in significantly higher ongoing pregnancy rates compared to 48 hours.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10
• Study First Submitted: 2012-03-27
• Study First Submitted QC: 2012-06-15
• Study First Posted: 2012-06-18
• Primary Completion: 2013-06
• Study Completion: 2013-06
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-17
• Last Update Posted: 2019-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 435

Inclusion Criteria

• below 39 years of age on the day of LH peak
• donor semen
• natural cycle (without CC)
• cycle with less than 3 follicles reaching 15 mm of diameter or more.
• with basal hormonal values of progesterone ( < 1,2 ng/dl)

Exclusion Criteria

The patients excluded are women

• who underwent more than 6 intrauterine inseminations,
• with tubal infertility

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	intra-uterine insemination	intrauterine insemination after 48 hours
Study group	intra-uterine insemination	intrauterine insemination after 24 hours

Primary Outcome Measures

Name	Time	Method
pregnancy rate	end of 2013 (up to 2 years)

Secondary Outcome Measures

Name	Time	Method
live birth rate	end of 2013 (up to 2 years)

Trial Locations

Locations (1)

Christophe Blockeel; 🇧🇪 Brussel, Belgium