Analysis of NK cell function in patients with multiple myeloma
Not Applicable
Recruiting
- Conditions
- Multiple myeloma
- Registration Number
- JPRN-UMIN000022764
- Lead Sponsor
- Division of Hematology National Center for Global Health and Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1)Who does not agree with the participation into the study. 2)Who can not understant the explanation about this study. 3)Who should be excluded judged by principal investigator.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To analyze the quantitive and qualitative status in patients with multiple myeloma. 1)The number of NK cells 2)Surface proteins 3)Cytotoxic activities 4)Response to cytokines in NK cells
- Secondary Outcome Measures
Name Time Method To evaluate the effect of monoclonal antibodies on NK cells. 1)Proliferation effects 2)Survival effects 3)Cytotoxic activities To evaluate the effect of NK cells on myeloma cells. 4)Cytotoxic activities of NK cells against myeloma cells 5)Effects of chemotherapy and stem cell transplantation on NK cells