Therapeutic effects of Motilitone in patient with constiptatio
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0001696
- Lead Sponsor
- Gachon University Gil Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
1) Patient, fully understands the purpose of the study and agrees participation in the study
2) Patinet, diagnosed with functional constipation by ROME III criteria
? Straining during at least 1/4 (25%) of defecations
? Lumpy or hard stools in at least 1/4 (25%) of defecations
? Sensation of incomplete evacuation for at least 1/4 (25 %) of defecations
? Sensation of anorectal obstruction/blockage for at least 1/4 (25%) of defecations
? Manual maneuvers to facilitate at least 1/4 (25%) of defecations (e.g., digital
acuation, support of the pelvic floor)
? Fewer than three defecations per week
Loose stools are rarely present without the use of laxatives
Insufficient criteria for irritable bowel syndrome
Criteria fulfilled for the last ? months with symptom onset at least ? months prior to diagnosis
1) Patient who have abnormal finding in ensocopic or radiographic exam, within 2 years
2) Patient with gastrointestinal surgery, except for appendectomy and restoration surgery of inguinal hernia in the past
3) Patient with severe liver function, renal function, cardiac function, pulmonary function, and other systemic problem
4) Patient with drug hypersensitivity for Motilitone
5) Patient with lactose intolerance
6) Improper patient in the study, according to judgement of researcher
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method colon transit time
- Secondary Outcome Measures
Name Time Method frequency of defecation;Degree of straining during defecation;Defecation form (according to Bristol scale);Degree about sensation of incomplete evacuation after defecation;Degree about sensation of anorectal obstruction during defecation;Abdominal discomfort;Satisfaction of defecation