The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Measure changes in citrate in urine.
研究概览
简要总结
This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
详细描述
The primary objective of this study is to determine whether a two-week course of daily ACV supplementation significantly changes an individual's urine chemistry. The investigators will study this in healthy individuals and individuals with kidney stones.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Controls: Adults above the age of
- •Kidney stone patients: Adults above the age of
- •History of majority (>50%) calcium oxalate kidney stones
排除标准
- •Anyone with a history of calcium phosphate stones (>50% calcium phosphate), uric acid stones, struvite stones, recent urinary tract instrumentation (<30 days), or recurrent urinary tract infections.
- •Any individual who has had ACV outside of normal consumption in the prior month will be excluded.
- •Any individual who has a history of a negative reaction (increased acid reflux, allergy) to ACV will also be excluded.
- •Any individual with chronic kidney disease, underlying acid base disorder will also be excluded.
研究组 & 干预措施
kidney stone patients and healthy participants
Each participant will be asked to complete a basic metabolic panel prior to initiating the study to ensure that no baseline metabolic derangements exist. On day 1, participants will complete a 24-hour urine collection and 48-hour food diary at home. Participants will then consume an ACV gummy containing 60 meq daily for 14 consecutive days.
干预措施: Apple Cider Vinegar (Dietary Supplement)
结局指标
主要结局
Measure changes in citrate in urine.
时间窗: From Enrollment to 2 weeks
to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
Measure changes in Urine PH
时间窗: From enrollment to 2 weeks
to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
Measure changes in calcium in urine.
时间窗: from enrollment to 2 weeks
to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
Measure changes in calcium oxalate in urine
时间窗: From Enrollment to 2 weeks
to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
次要结局
未报告次要终点