Static Arterial Elastance Ratio to Explain the Physiologic Meaning of Dynamic Arterial Elastance in Sepsis or Septic Shock

Completed

• Conditions: Sepsis or septic shock; dynamic arterial elastance, arterial elastance, sepsis, septic shock, arterial impedance, pulse pressure variation, and stroke volume variation.

• Registration Number: TCTR20230110003
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-09-20
• Study Start: 2023-01-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1) age older than 18 years old; 2) admission from the emergency department or general ward with sepsis or septic shock defined by The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); 3) on controlled mechanical ventilation, and 4) require fluid challenge by physician's discretion.

Exclusion Criteria

cardiac arrhythmia, valvular heart disease, intracardiac shunt, intra-abdominal hypertension, contraindication for sedation, contraindication for using a neuromuscular blocking agent, and pregnancy.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relationship At time of sepsis or septic shock Correlation coeficient

Secondary Outcome Measures

Name	Time	Method
Relationship to arterial elastance At time of sepsis or septic shock Correlation coefficient