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临床试验/CTRI/2025/09/095294
CTRI/2025/09/095294尚未招募2 期

Comparative pharmaceutico-clinical study of Karviradya Yoga for its altered form of tail and lotion for its efficacy on Kikwis in primi gravida

Dr Ashok Rajaram Vankalas1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年11月1日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To prepare Karviradya Tailam and Karviradya lotion by standard operating

研究概览

简要总结

Ayurveda is holistic system and science of life, which is practiced by many Vaidya. Ayurveda emphasize both prevention and treatment of disease. It offers numerous medicinal products with beautification properties, making them suitable for cosmetic use. Rasa Shastra and Bhaishajya Kalpna is crucial branch of Ayurveda that encompasses the study of medicines preparation, consumption methods, application and shelf life. The natural form of any medicine is often not practice for treatment, requiring modification through Kalpana. The branch of Ayurveda responsible for preparation and modifying medicine is called Bhaishajya Kalpana. It provide broad understanding of internal and external application of medicines such as Guti,Vati, Lepa, Avaleha, Sneha, Anjana, Malahara, Sandhana. A women is considered the embodiment of beauty created by Divine. Women plays a sacrade role in creation, nurturing and sustainance of life within the womb. Experiencing motherhood is a profound joy for every women, who anticipates a fruitful pregnancy and delivery. Therefore, it’s crucial to enhance the physical and mental health well-being of expectant mother. To achieve this our ancient scholar, have out lined guidelines know as ’Garbhini Paricharya’. Aacharya Vaghabhat, in particular has provided detailed insight into ’Garbhini Kikwis’1 and their management. Garbhini Kikwis, also known as Striae gravidarum are stretch marks that commonly appear during pregnancy, typically in the second trimester. They manifest with symptoms such as itching (Kandu), burning sensation (Daha) and discoloration (Vaivarnya). These marks are often observed particularly on the abdomen, breast region and thighs. Women are often very concern about their appearance and beauty, stretch marks can affect their self-confidence as they perceive them as making their appearance less attractive. Stretch marks appear as visible linear, pinkish scar that develop in areas where dermis has been damage due to excessive stretching of skin and weakening of elastic tissue.In the present era, there is a wide range of skin care products and innovative procedures available, including laser surgeries and dermabrasion. However, there is no promising treatment for striae gravidarum available in market, and this existing treatment can be expensive and invasive. Therefore, people are increasingly turning to Ayurveda in search of safer and more effective methods to address these troublesome stretch marks during pregnancy. Currently, there is no specific Ayurvedic lotion proven to be highly effective in eradication or improving stretch marks. The management of Kikwis is outlined in various ancient ayurvedic texts such as, Charak Samhita, Ashthang Hridya, Ashthang Sangrah and Bhel Samhita. Ayurveda recommend treatment like Aaushadhi sevana, Parisheka, Abhayanga, Lepa and Pathyapathya to alleviate the severity of Kikwis. Indeed, people are increasingly drawn to the convenience of topical application, such as Lotions, for their ease of use anytime and anywhere. Additionally, lotions are often cost effective and provide users with sense of mental satisfaction after application. NEED OF THE STUDY

  1. Currently there are less number of lotion formulated from Ayurvedic medicine specifically designed for Kikwis. 2.To enhance the absorption through the skin and alleviate the unpleasant odor associate with Sneha Kalpana prepared medicines, exploring modification is crucial.
  2. Evaluating the efficacy of their modification is essential for various external application across numerous disorders.
  3. The study aims to prepare Karviradya yoga and explore its modification into tail and lotion form.
  4. Both formulations will undergo evaluation and comparison for their effect on Kikwis to find better option between them. 6.Lotion formulation offer ease of use and application for patients and providing a convenient option that save time.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
21.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • Primigravida women.
  • Singleton pregnancy 20-22weeks of Gestational age at time of recruitment.
  • Absence of abdominal striae.
  • Age more than 21 years at recruitment.

排除标准

  • Multigravid women.
  • Preterm delivery.
  • Women who decline to discontinue other creams and lotion.
  • Women who unable to give consent.

结局指标

主要结局

To prepare Karviradya Tailam and Karviradya lotion by standard operating

时间窗: 0 day assessment onset | 1 st follow up on 28th day | 2 nd follow up on 56th day | 3 rd follow up on 84th day

procedure.

时间窗: 0 day assessment onset | 1 st follow up on 28th day | 2 nd follow up on 56th day | 3 rd follow up on 84th day

To observe the efficacy of tail form on kikwis in primi gravida.

时间窗: 0 day assessment onset | 1 st follow up on 28th day | 2 nd follow up on 56th day | 3 rd follow up on 84th day

To observe the efficacy of lotion form on kikwis in primi gravida.

时间窗: 0 day assessment onset | 1 st follow up on 28th day | 2 nd follow up on 56th day | 3 rd follow up on 84th day

次要结局

  • To observe the efficacy of tail form on kikwis in primi gravida.(To observe the efficacy of lotion form on kikwis in primi gravida.)

研究者

发起方
Dr Ashok Rajaram Vankalas
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Ashok Rajaram Vankalas

Shree Saptashrungi Ayurved Mahavidyalaya and Hosptal

研究点 (1)

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