Comparison of efficacy of erector spinae plane block with paravertebral block for postoperative pain management in patients undergoing breast cancer surgeries

Not Applicable

Not yet recruiting

Lead Sponsor: Safdarjung hospital and Vardhman Mahavir Medical College New Delhi India

Brief Summary: This study is aimed at comparing the efficacy of erectoe spinae plane block with paravertebral block for postoperative pain relief in patients undergoing breast cancer surgery.

Study will be conducted in adult females of age 18-60 years weighing>50 kgs fulfilling the criteria of ASA physical status I and II undergoing breast cancer surgery under general anaesthesia with controlled ventilation.

Patient taken to O.T. and baseline parameters of HR, BP, SPO2 noted.

Standard general anaesthesia administered, inj dexamethasone 0.1mg/kg given, inj paracetamol 1gm i.v. over 30 mins administered.

Randomized into two groups:

GROUP E (USG guided erector spinae block) in lateral position using 21 ml of 0.5% ropivacaine + clonidine 1mcg/kg made to total of 22ml.

GROUP P(USG guided paravertebral block) in lateral position using 21ml of 0.5% ropivacaine +1 mcg/kg clonidine made to total of 22ml.

Intraoperative fentanyl requirement to be noted

Parameters to be noted after reversal:

1.Duration of analgesia

2.VAS score

3.Total tramadol requirement

4.PONV score

5.Patient satisfaction using NRS

6.Intraoperative fentanyl requirement

Recruitment & Eligibility

Inclusion Criteria

This study will be conducted in adult female patients of age 18.
60 years weighing > 50 kgs, fulfilling criteria of American Society of Anaesthesiology (ASA) physical status i and ii undergoing elective modified radical mastectomy (MRM) for breast cancer under general anaesthesia with controlled ventilation.

Exclusion Criteria

Primary Outcome Measures

Name	Time	Method
Duration of Analgesia- time from administration of the block till time of administration of first rescue analgesia to the patient will be noted (primary objective).	Preoperative vitals to be noted at time 0. \| Intraoperative vitals to be noted at before block, 10, 20, 30, 40, 50, 60, 90, 120, 150, 180 mins after the block. \| postoperative: \| 1. VAS assessment at 0,1,2,4,6.,12,24 hours \| 2. PONV score assessed at 0,6,12,24 hours.

Secondary Outcome Measures

Name	Time	Method
1) Visual Analogue Scale (VAS)	2) Total intraoperative requirement of fentanyl

Locations (1): Safdarjung Hospital and Vardhmann Mahavir Medical College New Delhi 110023
🇮🇳
Delhi, DELHI, India
Safdarjung Hospital and Vardhmann Mahavir Medical College New Delhi 110023
🇮🇳Delhi, DELHI, India
Arjun Singh
Principal investigator
9560316794
arjun.mander95@gmail.com