Comparing sodium hyaluronate effects on eye moisture after cataract surgery
- Conditions
- Dry eye syndrome, meibomian gland dysfunctionEye Diseases
- Registration Number
- ISRCTN95830348
- Lead Sponsor
- Pusan National University Yangsan Hospital
- Brief Summary
2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39078835/ (added 31/07/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 70
1. Be male or female, aged 19 years to 90 years
2. Have a tear breakup time (TBUT) of 10 seconds or more
3. Have a Schirmer’s I test result of 10 mm or more
4. Have not used diquafosol-based eye drops, artificial tear drops, steroid eye drops, or antibiotic eye drops within 3 months before participation
5. Show normal blinking during a slit lamp exam
6. Voluntarily agree to participate in this study
1. Has Sjögren's syndrome
2. Has severe blepharitis
3. Had ocular surgery or laser eye surgery
4. Has severe ocular inflammation/infection
5. Is using eye drop treatment for dry eyes, such as glaucoma or allergies
6. Shows sensitivity to the study drugs
7. Is considered to be ineligible for participation owing to reasons other than the aforementioned exclusion criteria based on the judgment of the principal researcher
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measured at baseline (1 week before cataract surgery) and 1, 3, 6 weeks after cataract surgery:<br>1. Ocular surface status parameters:<br>1.1. Lipid layer thickness (LLT) measured using an interferometer<br>1.2. Schirmer’s type I test using COLOR BAR by Eagle Vision Inc.<br>1.3. Tear breakup time (TBUT), corneal staining score(CSS), meiboscore were measured by an ophthalmologist<br>2. Patients’ symptoms measured using Ocular Surface Disease Index (OSDI) questionnaire
- Secondary Outcome Measures
Name Time Method There are no secondary outcome measures