Affective Processing in Depression and Epilepsy; An fMRI Study

Northwell Health1 site in 1 country14 target enrollmentJune 2008

ConditionsEpilepsy Depression Healthy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Epilepsy
Sponsor: Northwell Health
Enrollment: 14
Locations: 1
Status: Terminated
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this study is to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.

Detailed Description

Symptoms of depression is commonly seen in patients with epilepsy. There are similarities and differences between depressive symptoms in epilepsy when compared with primary depression. Through the use of fMRI (Functional MRI), we hope to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.

Registry

clinicaltrials.gov

Start Date

June 2008

End Date

June 2009

Last Updated

16 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Northwell Health

Eligibility Criteria

Inclusion Criteria

•Healthy adults of 18 years of age or older.

Exclusion Criteria

•Subject has no history of affective disorders
•Subject scores higher than 5 on Hamilton Depression Rating Scale
•Subject with prior primary diagnosis of any psychotic disorder, bipolar disorder, anxiety disorder, or any other serious medical or neurological disorder
•Subject is pregnant
•Subject is unable to undergo a MRI
•Epilepsy Only Group
•Inclusion Criteria:
•Subject is at least 18 years of age
•Subject has confirmed temporal lobe epilepsy (TLE)
•Exclusion Criteria: