Evaluation of Efficacy and Safety of Epidural Steroid Injection using Dexamethasone or Betamethasone in patients with spinal pain: a Prospective, Randomized, Double-blind, Cross-over study.
- Conditions
- Not Applicable
- Registration Number
- KCT0001912
- Lead Sponsor
- Seoul National University Bundang Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 600
Eligible patients were all adults aged 19 or over with sustained cervical or lumbar pain of 5 or over in pain intensity using Visual Analog Scale, irresponsive to conservative treatment, all who were referred for epidural steroid injection from orthopedic surgeons or neurosurgeons of spine-specialized center in our hospital.
Exclusion criteria were; (1) absolute or relative contraindication to the ESI (uncontrolled coagulopathy, uncontrolled diabetes mellitus, active systemic or local infection, and allergy to contrast medium or injected drugs), (2) history of adverse event after epidural steroid injection, (3) pregnancy or nursing, (4) participated in other study using ESI, and (5) underwent ESI in current 2 weeks.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method number of the responders with the effective pain relief showing no pain or much improved in subjective satisfaction
- Secondary Outcome Measures
Name Time Method number of crossover injection ;change of pain intensity (visual analog scale, VAS) compared to baseline;change of disability index (ODI and NDI) compared to baseline;adverse event