NCT06316895招募中不适用
The Clinical Outcomes and Artificial Intelligence Prediction Model of Ultrasound-guided Thermal Ablation for the Treatment of Low-risk Papillary Thyroid Carcinoma
Chinese PLA General Hospital1 个研究点 分布在 1 个国家目标入组 3,772 人开始时间: 2024年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,772
- 试验地点
- 1
- 主要终点
- rate of disease progression
研究概览
简要总结
- To evaluate the clinical outcomes of ultrasound-guided thermal ablation and thyroid surgery for the treatment of papillary thyroid carcinoma;
- To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of papillary thyroid carcinoma;
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients age between 18 and 80 year old, both sex
- •papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
- •the largest diameter ≤2.0 cm
- •no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, nech and chest CT
- •follow-up period ≥12 months,
排除标准
- •patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
- •history of neck radiation
- •history of thyroid surgery
- •coagulation disorder
- •serious heart, respiratory, liver, or renal failure
- •dysfunction of the vocal cord on the opposite side
结局指标
主要结局
rate of disease progression
时间窗: more than 5 year
cervical lymph node metastases, recurrent tumors and persistent tumors
次要结局
- Rate of complications(1week)
- Rate of tumor disappearance(2 year)
研究者
Yu-kun Luo
Director, Head of Department of Ultrasound
Chinese PLA General Hospital
研究点 (1)
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