Anaerobic Power and Salbutamol

Not Applicable

Completed

• Conditions: Ergogenic Athletic Performance
• Interventions: Other: Cycling Exercise

• Registration Number: NCT02255630
• Lead Sponsor: University of British Columbia

Brief Summary

Athletes using inhaled β2-adrenoreceptor agonists (IBAs) win a disproportionate number of medals. However, most previous research has shown that β2 agonists do not improve exercise performance in either asthmatic or non-asthmatic athletes. Although the majority of these studies do not show an ergogenic effect, the small number of studies with extended exercise bouts (\~60 minutes) do show an advantage. The investigators believe that a controlled yet sport-specific exercise protocol will elucidate this ergogenic effect. Because IBAs may have different effects on these two groups of athletes, the investigators will measure exercise performance in both female and male elite cyclists. The investigators hypothesize that athletes will perform better during a combination steady-state/sprint exercise task following salbutamol administration.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-09-16
• Study First Submitted QC: 2014-09-29
• Study First Posted: 2014-10-02
• Study Start: 2015-01
• Primary Completion: 2015-11
• Study Completion: 2016-08
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-09
• Last Update Posted: 2016-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• maximal oxygen consumption of ≥60 and ≥55 mL⋅kg-1⋅min-1 or ≥5⋅L⋅min-1 and ≥4⋅L⋅min-1 for men and women

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Exclusion Criteria

• pregnant women
• any history of uncontrolled respiratory or cardiac disease
• smokers
• diabetics

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Salbutamol inhalation	Cycling Exercise	Study participants will be exposed to 1600ug salbutamol 30min prior to exercise
Placebo inhalation	Cycling Exercise	Study participants will be exposed to 1600ug salbutamol 30min prior to exercise

Primary Outcome Measures

Name	Time	Method
Peak Power Output	peak power output of the final 30 seconds of the cycling bout will be assessed.

Trial Locations

Locations (1)

University of British Columbia, Environmental Physiology Laboratory; 🇨🇦 Vancouver, British Columbia, Canada