Quantitative EEG as biomarker for the prediction of seizures, depression and cognitive decline after stroke - A substudy to the Berling Longterm Observation of Vascular Events - BeLOVE - Study

Recruiting

• Conditions: I63.9; G40.9; Cerebral infarction, unspecified; Epilepsy, unspecified

• Registration Number: DRKS00017079
• Lead Sponsor: Charité Campus Benjamin Franklin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 625

Inclusion Criteria

acute cerebrovascular disorders (trigger event), defined by:
i) a transient ischemic attack (TIA) with clinical restitution within 24h AND
initial neurological deficit verified by a neurologist OR ABCD2-Score >= 3 OR
visibleDWI-lesion (MRI) OR the main hospital diagnosis of Amaurosis fugax
ii) Ischemic stroke including retinal central artery occlusion
iii) stroke caused by non-traumatic intracerebral hemorrhage
iv) stroke caused by cerebral venous thrombosis

Exclusion Criteria

Epileptic seizure prior to the event leading to inclusion in the study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1st: Development of seizures, diagnosed using Epilepsy-Screening questionnaire by Ottman et al.<br>2nd: Development of Post-Stroke Depression using PHQ-9 questionnaire<br>3rd: Development of post-stroke cognitive decline using Montreal cognitive assessment (MOCA)-test<br>

Secondary Outcome Measures

Name	Time	Method
Development of acute symptomatic seizures within 7 days after the cerebrovascular event