The correlation between D-dimer Levels and Overall Survival in Newly-Diagnosed Adult Acute Leukemia in Siriraj Hospital

Completed

• Conditions: ewly diagnosed acute leukemia patients between March 2014 and December 2020; Acute leukemia; Bleeding; D-dimer; DIC; Disseminated intravascular coagulation; Hemorrhage; Thrombosis

• Registration Number: TCTR20230404004
• Lead Sponsor: Siriraj Hospital Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-04-03
• Study Start: 2023-04-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 261

Inclusion Criteria

1. Newly diagnosed acute leukemia patients between March 2014 and December 2020.
2. Participants had to be 15 or older and have been recently diagnosed with acute leukemia, including ALL, APL, and AML.

Exclusion Criteria

1.The patients with familial thrombophilia.
2.using antiplatelet or anticoagulant agents before their acute leukemia diagnosis.
3. without DIC-related laboratory results at diagnosis.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of baseline characteristics and outcomes of individual acute leukemia subtypes First clinic visit Result of the individual acute leukemia subtype.

Secondary Outcome Measures

Name	Time	Method
Comparison of baseline characteristics of thrombohemorrhagic and non-thrombohemorrhagic groups First clinic visit Result of fibrinogen