Effect of eyelid wipes with Manuka honey on ocular signs and symptoms

Not Applicable

Recruiting

• Conditions: Dry eyes; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12622000334707
• Lead Sponsor: SW Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-02-23
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

•Adult aged 18 years of older
•Able to read and comprehend English and give informed consent as demonstrated by signing a record of informed consent
•Symptoms of dry eye (OSDI questionnaire score of >12)
•At least one sign of dry eye in one eye (e.g. blocked oil-producing gland on the eyelid margin, average fluorescein tear break-up time <10 seconds)
•Willingness to not change usage frequency and type of any currently used products for the treatment of dry eye for the duration of the study

Exclusion Criteria

•Known allergy to honey/bee products
•Hard contact lens wear one month prior to baseline and during the study, or soft contact lens wear one week prior to baseline and during the study
•Use of eyelid cosmetics during the study
•Have autoimmune disease or other systemic disease that may have an impact on tear film properties
•Use of any medication (eg. anti-inflammatory, anti-infectives or immunosuppressives) that may have an effect on ocular physiology and/or function during the study
•Active eye infection
•Use of Blephadex Pro eyelid wipes or any other ocular treatments (topical drops or creams) containing Manuka honey within 2 weeks prior to the Screening visit

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Microbial contamination on the eyelid margin.<br>A sterile cotton bud moistened with saline will be used to swab the edge of the eyelid. Samples will be stored in a sterile vial and transferred to the Microbiology lab, where bacteria will be cultured and counted.[One month post-intervention commencement.]

Secondary Outcome Measures

Name	Time	Method
Ocular symptoms measured using the Ocular Surface Disease Index questionnaire.[One month post-intervention commencement.]