The protective effect of azelastine/fluticasone propionate (Dymista) on exercise-induced airway obstructio

Phase 4

Recruiting

• Conditions: bovenste luchtwegaandoeningen, allergische rhinitis; asthma; exercise-induced asthma; 10024967

• Registration Number: NL-OMON48838
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 64

Inclusion Criteria

- Clinical history of allergic rhinitis and EIB
- Age between 12 and 18 years.
- Ability to perform spirometry and FOT

Exclusion Criteria

- Other pulmonary or cardiac illnesses
- Severe EIB i.e. a fall of >=40% FEV1 in the first ECT, requiring an acute change in maintenance medication (standard care)
- Use of long acting bronchodilator agents 24 hours before testing
- Use of short acting bronchodilator agents 8 hours before testing
- Hospitalization due to asthma exacerbation in the last 4 weeks
- Use of intranasal or systemic corticosteroids in the last 4 weeks prior to the study.
- Use of antihistamines, cromoglycates, anticholinergics in two weeks prior the study or during the study.
- Other changes in asthma medication during treatment period
- Insufficient knowledge of the Dutch language

Study & Design

• Study Type: Interventional
• Study Design: Not specified