Evaluation of the H-coil Transcranial Magnetic Stimulation TMS Device - Safety and Feasibility Study for Acute and Maintenance Treatment in Major Depressive Episode
Phase 2
Completed
- Conditions
- Major Depressive Disorder
- Registration Number
- NCT00807105
- Lead Sponsor
- Shalvata Mental Health Center
- Brief Summary
This is a prospective open label study of acute and maintenance treatment of MDD. The acute phase consists of daily treatments for 4 weeks. maintenance will be twice a week for eight weeks followed by 10 weeks of once a week treatments.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
- MDD patients
Exclusion Criteria
- risk factors for convulsions
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method response in HAMDS 1 YEAR
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie H-coil dTMS effects on prefrontal cortex activity in Major Depressive Disorder?
How does H-coil dTMS compare to ECT and SSRI therapy in acute MDD treatment outcomes and relapse prevention?
Which neuroimaging or genetic biomarkers predict response to H-coil dTMS in treatment-resistant depression subtypes?
What adverse event profiles are reported for H-coil TMS versus conventional TMS in Phase 2 MDD trials?
Are there combination therapies involving H-coil dTMS and glutamatergic modulators for enhanced MDD treatment efficacy?
Trial Locations
- Locations (1)
ShalvataMHC
🇮🇱Hod Hasharon, Israel
ShalvataMHC🇮🇱Hod Hasharon, Israel