The effects of aerobic and resistance exercise on metabolic parameters of type 2 diabetes mellitus
- Conditions
- Endocrine, nutritional and metabolic disease
- Registration Number
- KCT0004671
- Lead Sponsor
- Pusan National University Hospital
- Brief Summary
In the EXE group, Apolipoprotein J (Apo J) levels decreased 26.3% and 19.4%, relative to baseline, at 8 and 12 weeks, respectively. Between-group differences were significant at 8 and 12 weeks (P<0.05 and P<0.001, respectively). In the EXE group, 12 weeks of exercise resulted in significant decreases in body weight, percent body fat, and HOMA-IR indices. Concurrently, weight-adjusted appendicular skeletal muscle mass (ASM/wt) was increased in the EXE group compared with the CON group. Importantly, changes in the ApoJ level were significantly correlated with changes in ASM/wt.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 45
Type 2 diabetes mellitus
Postmenopausal women
(1) active infection within the past month
(2) a recent history of acute myocardial infarction, stroke, trauma, or surgery
(3) neoplastic disorder
(4) occlusive peripheral vascular disease
(5) severe liver dysfunction
(6) taking antidepressants or neurotrophic drugs
(7) Alzheimer’s disease
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Metabolic parameter of serum and urine
- Secondary Outcome Measures
Name Time Method Body composition