Effect of vasopressin in sick babies with low blood pressure
Not Applicable
- Conditions
- Health Condition 1: P299- Cardiovascular disorder originating in the perinatal period, unspecified
- Registration Number
- CTRI/2022/12/048258
- Lead Sponsor
- Dr Anup Thakur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All neonates with refractory shock who received vasopressin infusion at least for 24
hours from January 2016 to May 2021 will be included.
Exclusion Criteria
Neonates with congenital heart diseases
or other lethal anomalies and those in whom data retrieval is inadequate will be excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Systolic, mean and diastolic blood pressure at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy- Blood pressure recordings will be retrieved from nursesâ?? chart. Invasive blood pressure readings will be considered whenever available. <br/ ><br>2.Heart rate at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. <br/ ><br>3.Urine output at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. <br/ ><br>4.Biochemical parameters such as pH, bicarbonate levels, base deficit, lactate and sodium levels before and in first 72 hours of vasopressin administration. Worst parameters will be taken. <br/ ><br>5.Inotrope score at baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy. <br/ ><br>6.Oxygenation index at baseline and during first 72 hours of vasopressin therapy. Worst parameters will be taken. <br/ ><br>Timepoint: baseline, 6, 12, 24, 48 and 72 hours of vasopressin therapy
- Secondary Outcome Measures
Name Time Method not applicableTimepoint: not applicable